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Gout is a type of arthritis caused by monosodium urate crystals forming inside and around joints, causing sudden flares of severe pain, heat, and swelling. Any joint can be affected, but it most … NICE recommends confirming clinical diagnosis by measuring serum urate level (>360μmol/l). If < 360μmol/l during flare and gout still strongly suspected repeat level 2 weeks after flare has settled. Acute gout presents with an abrupt onset of pain, swelling and erythema, most commonly (up to 78% of first attacks) affecting the great toe (podagra). Other joints that are frequently affected include … Based on systematic reviews, consideration of cost effectiveness and the committee's clinical experience, this NICE guideline list number of recommendations for diagnosis and management of … Scenario: Preventing gout: Covers the principles of gout prevention and includes information on prophylactic drug treatment. The content on the NICE Clinical Knowledge Summaries site (CKS) is … During a gout attack, it is important to rest, raise the limb and avoid knocking or damaging the affected joint. Ice packs also help. Septic arthritis is suspected, then referral to A&E is required. Covers the principles of gout prevention and includes information on prophylactic drug treatment. In some patients, the frequency and duration of acute attacks increases over time and leads to chronic gout, which may be associated with deposits of uric acid crystals known as tophi. Affected joints … Covers the management of an acute attack of gout and includes advice on what to do if treatment fails and recommended follow-up. Gout is usually monoarticular but can be oligoarticular or rarely polyarticular. Symptom severity and speed of onset — rapid onset of severe pain with associated swelling, redness, warmth and …